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KMID : 0357820030270020023
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Korean Journal of Legal Medicine
2003 Volume.27 No. 2 p.23 ~ p.30
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Development of Multi-tissue Array Block for Diagnosis of Early Myocardial Infarction
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Ha Hong-Il
Li Zhe
Kim Jang-Han
Lee Yoon-Seong
Lee Jung-Bin
Lee Soong-Deok
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Abstract
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Tissue array contains hundreds or thousands tissues from different cases, and has been known useful for rapid analysis of markers in a large numbered work. This has mainly been used in investigative purpose, and few has been reported for diagnostic trial. Diagnosis of early myocardial infarction is important in medicolegal field. Immunohistochemical staining using various antibodies has become a popular tool for this purpose, but standardization and reproducibility have been problems. Use of tissue array is promising in this points. We have made two cardiac tissue arrays using 87 different cases and have verified the feasibility of tissue array in forensic field. Experiences and several issues concerning tissue array are discussed.
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KEYWORD
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Tissue array, Heart, Early myocardial infarction, Immunohistochemistry
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